Simponi Aria
Simponi Aria is an anti-tumor necrosis factor (TNF) biologic medication. Inflammatory conditions such as rheumatoid arthritis, psoriatic arthritis, and ankylosing spondylitis are caused by an overactive immune system. The immune system mistakenly attacks the body's own tissues, leading to inflammation, pain, and other symptoms. TNF is a protein that is involved in the immune system's response to inflammation. It is produced by certain cells in the body and helps to regulate the inflammatory process. However, in people with inflammatory conditions, TNF is produced in excess, leading to chronic inflammation.
Order FormWhat does Simponi Aria Treat?
- Moderate to severe rheumatoid arthritis
- Ankylosing spondylitis
- Psoriatic arthritis
Treatment Cycle and Duration
Cycle: Given weeks 0, 4, and every 8 weeks thereafter.
Duration: 30 minutes
Side Effects
Upper respiratory tract infection
Elevated liver enzymes
Viral infection
Bronchitis
Elevated blood pressure
Increased risk of infection
How Does Simponi Aria Work?
TREATMENT EDUCATION
Simponi Aria works by blocking TNF, which helps to reduce inflammation and relieve the symptoms of inflammatory conditions. By reducing inflammation, Simponi Aria can also help slow down the progression of these conditions.
What to Expect During Your Infusion
Before your infusion, it is important to drink plenty of water and come to your appointment hydrated. Additionally, you must alert us as soon as possible to any changes in your insurance to ensure that we are still an in-network provider for your infusion therapy.
- Pure doesn’t believe in waiting rooms. You’ll be taken to your own private suite where you’ll check in and your nurse will take your vitals and complete a pre-infusion assessment.
- To begin the infusion, an IV line will be inserted into your arm or hand. The medication will be connected and the nurse will monitor the infusion carefully, especially the first few minutes, to watch for reactions or side effects and make sure you’re comfortable.
- When the infusion is complete, your IV will be removed and the nurse will apply a bandage. Your nurse will give you instructions on side effects to watch for and when to seek help. You may be asked to stay for a short observation period.
- You can resume normal activities, though you may feel tired or need to rest. Drink water and eat a light meal to help with fatigue or nausea.

Why Patients Choose to Receive Simponi Aria at Pure Infusion
Safe and private suites
You’ll have your own spa-like atmosphere with 55-inch TV, streaming options, WiFi, refreshments, meals, and more.
Expert medical staff
Our team takes care of the insurance pre-authorization, offers co-pay and financial assistance, and ensures your visit meets your unique needs.
Patient assitance
Specializing in infusion care for MS, Crohn’s, Colitis and many others. See the full list below and ask your provider about switching to Pure.
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