Rituxan
What does Rituxan Treat?
- Non-Hodgkins Lymphoma
- Chronic lymphocytic leukemia
- Rheumatoid arthritis
- Granulomatosis with polyangiitis (GPA)
- Microscopic polyangiitis (MPA)
- Pemphigus Vulgaris (PV)
Treatment Cycle and Duration
Cycle: As prescribed by physician
Duration: 3-4 hours
Side Effects
Infusion-related reaction
Headache
Increased risk of infection
Nasopharyngitis
Upper respiratory tract infection
How Does Rituxan Work?
TREATMENT EDUCATION
Rituxan works by targeting the CD20 antigen on normal cells and B-cells, then the body’s natural immune defenses are recruited to attack and kill the marked B-cells. In NHL and CLL, B-cells can become cancerous and multiply uncontrollably. By destroying these cancerous B-cells, Rituxan can help to slow or stop the progression of the disease. In RA and vasculitis, B-cells play a role in the autoimmune response that causes inflammation and tissue damage. By targeting and destroying these B-cells, Rituxan can help to reduce inflammation and slow the progression of these diseases. Stem cells (young cells in the bone marrow that will develop into the various types of cells) do not have the CD20 antigen. This allows healthy B-cells to regenerate after treatment.
What to Expect During Your Infusion
- Pure doesn’t believe in waiting rooms. You’ll be taken to your own private suite where you’ll check in and your nurse will take your vitals and complete a pre-infusion assessment.
- To begin the infusion, an IV line will be inserted into your arm or hand. The medication will be connected and the nurse will monitor the infusion carefully, especially the first few minutes, to watch for reactions or side effects and make sure you’re comfortable.
- When the infusion is complete, your IV will be removed and the nurse will apply a bandage. Your nurse will give you instructions on side effects to watch for and when to seek help. You may be asked to stay for a short observation period.
- You can resume normal activities, though you may feel tired or need to rest. Drink water and eat a light meal to help with fatigue or nausea.
