Nucala
Nucala is a humanized monoclonal antibody that targets human Interleukin-5 (IL-5), it is indicated for add on maintenance treatment of patients 6 years and older with severe asthma with eosinophilic phenotype. Inflammation is an important component of asthma development. It is mediated by multiple cell types which include eosinophils, a type of white blood cell that protects the body from parasites, allergens and foreign bacteria. Eosinophilic inflammation can be characterized by high eosinophilic count via bloodwork. IL-5 is a major cytokine which is responsible for eosinophil development.
Order FormWhat does Nucala Treat?
- Severe asthma with an eosinophilic phenotype
- Chronic rhinosinusitis with nasal polyps (CRSwNP)
- Eosinophilic granulomatosis with polyangiitis (EGPA)
- Hypereosinophilic syndrome (HES)
Treatment Cycle and Duration
Cycle: Every 4 weeks
Duration:
Side Effects
Hypersensitivity reaction
Headache
Injection site reaction
Back pain
Fatigue
Joint pain
How Does Nucala Work?
TREATMENT EDUCATION
Nucala binds and targets IL-5 blocking. IL-5 binds to the alpha chain of the IL-5 receptor complex. This prevents IL-5 signaling, reducing the production and survival of eosinophils.
What to Expect During Your Infusion
Before your infusion, it is important to drink plenty of water and come to your appointment hydrated. Additionally, you must alert us as soon as possible to any changes in your insurance to ensure that we are still an in-network provider for your infusion therapy.
- Pure doesn’t believe in waiting rooms. You’ll be taken to your own private suite where you’ll check in and your nurse will take your vitals and complete a pre-infusion assessment.
- To begin the infusion, an IV line will be inserted into your arm or hand. The medication will be connected and the nurse will monitor the infusion carefully, especially the first few minutes, to watch for reactions or side effects and make sure you’re comfortable.
- When the infusion is complete, your IV will be removed and the nurse will apply a bandage. Your nurse will give you instructions on side effects to watch for and when to seek help. You may be asked to stay for a short observation period.
- You can resume normal activities, though you may feel tired or need to rest. Drink water and eat a light meal to help with fatigue or nausea.
Why Patients Choose to Receive Nucala at Pure Infusion
Safe and private suites
You’ll have your own spa-like atmosphere with 55-inch TV, streaming options, WiFi, refreshments, meals, and more.
Expert medical staff
Our team takes care of the insurance pre-authorization, offers co-pay and financial assistance, and ensures your visit meets your unique needs.
Patient assitance
Specializing in infusion care for MS, Crohn’s, Colitis and many others. See the full list below and ask your provider about switching to Pure.
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