Krystexxa
Krystexxa (pegloticase) is an enzyme made to specifically target uric acid in the treatment of chronic gout. Krystexxa is used for patients that have failed to have success with other treatments. Uric acid is created when the body breaks down purines, a chemical compound that cells use to make DNA and RNA. Purines can also be ingested as they are found in high purine foods such as some seafood, meats, alcohol, and sweet drinks. In normal amounts, uric acid is passed through the urinary tract to exit the body. When the kidneys are unable to remove enough excess uric acid from the bloodstream, it results in hyperuricemia. The uric acid clumps together forming crystals. These crystals prefer to accumulate in joints, especially in the hands and feet, a condition known as gout.
Order FormWhat does Krystexxa Treat?
- Severe chronic gout
Treatment Cycle and Duration
Cycle: Every 2 weeks
Duration: 2 hours
Side Effects
Gout flare
Infusion reaction
Allergic reaction
Nausea
Vomiting
Bruising
Chest pain
Sore throat
Constipation
How Does Krystexxa Work?
TREATMENT EDUCATION
Krystexxa is given to treat severe, treatment-refractory, chronic gout because the enzyme converts uric acid into allantoin, a water-soluble substance the body can easily excrete. This process decreases uric acid levels in the blood, and over time Krystexxa dissolves uric acid crystal buildup, relieving gout symptoms and flares.
What to Expect During Your Infusion
Before your infusion, it is important to drink plenty of water and come to your appointment hydrated. Additionally, you must alert us as soon as possible to any changes in your insurance to ensure that we are still an in-network provider for your infusion therapy.
- Pure doesn’t believe in waiting rooms. You’ll be taken to your own private suite where you’ll check in and your nurse will take your vitals and complete a pre-infusion assessment.
- To begin the infusion, an IV line will be inserted into your arm or hand. The medication will be connected and the nurse will monitor the infusion carefully, especially the first few minutes, to watch for reactions or side effects and make sure you’re comfortable.
- When the infusion is complete, your IV will be removed and the nurse will apply a bandage. Your nurse will give you instructions on side effects to watch for and when to seek help. You may be asked to stay for a short observation period.
- You can resume normal activities, though you may feel tired or need to rest. Drink water and eat a light meal to help with fatigue or nausea.
Why Patients Choose to Receive Krystexxa at Pure Infusion
Safe and private suites
You’ll have your own spa-like atmosphere with 55-inch TV, streaming options, WiFi, refreshments, meals, and more.
Expert medical staff
Our team takes care of the insurance pre-authorization, offers co-pay and financial assistance, and ensures your visit meets your unique needs.
Patient assitance
Specializing in infusion care for MS, Crohn’s, Colitis and many others. See the full list below and ask your provider about switching to Pure.
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