Tepezza
Tepezza is a biologic drug that is the first and only FDA-approved medication used to treat thyroid eye disease (TED). Behind your eyes there are tissues with cells that have receptors on their surface that act like light switches. When you have TED your body's immune system attacks this tissue which causes molecules known as auto antibodies to turn these switches on. This leads to swelling to the muscle and fat. This in turn causes eye pain, redness around the eyes, and swollen eyelids. The swollen muscle and fat tissue behind the eye can make eyes bulge and cause double vision.
Order FormWhat does Tepezza Treat?
- Thyroid Eye Disease
Treatment Cycle and Duration
Cycle: Once every 3 weeks for a total of 8 infusions
Duration: 60 to 90 minutes
Side Effects
Infusion reactions
Muscle spasm
Nausea
Hair loss
High blood sugar
Fatigue
Changes in taste
Dry skin
How Does Tepezza Work?
TREATMENT EDUCATION
Tepezza is designed to bind to the switch and block it from staying on. The two main mediators in TED are thyroid stimulating hormone receptor (TSHR) and insulin growth like factor 1 receptor (IGFR-1). In TED autoantibodies activate the IGFR-1R and TSHR signaling complex which stimulate orbital fibroblasts. Orbital fibroblasts are thought to be the cause of the severe inflammation and expansion of muscle and fat behind the eye. Tepezza blocks the IGFR-1R.
What to Expect During Your Infusion
Before your infusion, it is important to drink plenty of water and come to your appointment hydrated. Additionally, you must alert us as soon as possible to any changes in your insurance to ensure that we are still an in-network provider for your infusion therapy.
- Pure doesn’t believe in waiting rooms. You’ll be taken to your own private suite where you’ll check in and your nurse will take your vitals and complete a pre-infusion assessment.
- To begin the infusion, an IV line will be inserted into your arm or hand. The medication will be connected and the nurse will monitor the infusion carefully, especially the first few minutes, to watch for reactions or side effects and make sure you’re comfortable.
- When the infusion is complete, your IV will be removed and the nurse will apply a bandage. Your nurse will give you instructions on side effects to watch for and when to seek help. You may be asked to stay for a short observation period.
- You can resume normal activities, though you may feel tired or need to rest. Drink water and eat a light meal to help with fatigue or nausea.
Why Patients Choose to Receive Tepezza at Pure Infusion
Safe and private suites
You’ll have your own spa-like atmosphere with 55-inch TV, streaming options, WiFi, refreshments, meals, and more.
Expert medical staff
Our team takes care of the insurance pre-authorization, offers co-pay and financial assistance, and ensures your visit meets your unique needs.
Patient assitance
Specializing in infusion care for MS, Crohn’s, Colitis and many others. See the full list below and ask your provider about switching to Pure.
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