Entyvio
What does Entyvio Treat?
- Ulcerative colitis
- Crohn’s disease
Treatment Cycle and Duration
Cycle: Given at week 0, 2, 6, and then every 8 weeks
Duration: 30 minutes
Side Effects
Headache
Joint pain
Nausea
Fever
Fatigue
Upper respiratory tract infection
Increased risk of infections
Rash
Infusion site reaction
How Does Entyvio Work?
TREATMENT EDUCATION
People with Crohn’s and ulcerative colitis (UC) have an excess of white blood cells that target the gastrointestinal (GI) tract. The alpha-4-beta-7 T-cell attaches to the MAdCAM-1 receptor in the gut, causing increased inflammation. Entyvio belongs to a class of drugs known as monoclonal antibodies and works by blocking this connection so that excess white blood cells can’t enter the gut tissue. Entyvio is very specialized to specifically target GI proteins only. When T-cells can’t enter the gut, inflammation is reduced as well as the symptoms of Crohn’s and UC.
What to Expect During Your Infusion
- Pure doesn’t believe in waiting rooms. You’ll be taken to your own private suite where you’ll check in and your nurse will take your vitals and complete a pre-infusion assessment.
- To begin the infusion, an IV line will be inserted into your arm or hand. The medication will be connected and the nurse will monitor the infusion carefully, especially the first few minutes, to watch for reactions or side effects and make sure you’re comfortable.
- When the infusion is complete, your IV will be removed and the nurse will apply a bandage. Your nurse will give you instructions on side effects to watch for and when to seek help. You may be asked to stay for a short observation period.
- You can resume normal activities, though you may feel tired or need to rest. Drink water and eat a light meal to help with fatigue or nausea.
